Research projects

Research projects of Oral and Maxillofacial Surgery Research Center

Row	Title of research projects
1	*Prevalence of facial fractures in patients referring to Shariati Hospital in Tehran 90*
2	*Prevalence of cardiovascular disease in patients with obstructive sleep apnea*
3	*Accuracy Astryvftvgramtry system Kranyvmagzylvfyshyal Research Center, Tehran University of Medical Sciences*
4	*Effects of orthognathic surgery on quality of life*
5	*Cephalometric study of anatomical structures adjacent upper airway in patients with obstructive sleep apnea*
6	Evaluation of facial soft tissue changes with structured light technique to predict the results of orthognathic surgery (BiMax) Class III and three-dimensional modeling software design and implementation
7	*Histologic and histomorphometric effects of alendronic acid and calcium on Astyvayntgryshn femoral implants in rats was Avrktvmy*
8	*Induced bone formation in cleft palate using bone inducing protein (BMP-2) in dogs.*
9	*Examine factors associated with temporomandibular disorders in patients referred to the department of oral and maxillofacial surgery, Shariati Hospital*
10	*Investigate the correlation of clinical and pathological margin squamous cell carcinoma of the mouth*
11	*Measured anthropometric soft tissue in the adult population of Iranian foreign*
12	*Effect of cinching techniques in pre-surgical nasal lefort I*
13	*Prevalence and associated factors in patients with orofacial pain center in Tehran University Hospital*
14	*The effect of the synthetic membrane around the mandibular reconstruction plates on the amount of exposure*
15	*Evaluation and comparison of the lab and tissue toxicity caused by miniplates common in skull and maxillofacial surger.*
16	*IN silico design and production of the carrier structure (RECOMBINANT HUMAN BONE MOROHOGENETIC PROTEIN-2 (RHBMP-2 using genetic engineering in bacteria E.Coli*
17	*Expression of genes involved (DKK-1, BMP, β-catenin, sclerostin and Noggin) on routes bone growth in patients with unilateral development of temporomandibular joint condyle.*
18	*Optimize the BMP2 protein expression in E.Coli host*
19	*Pvrmvrfamyn the effect on osteogenic differentiation of endometrial stem cells on scaffolds of collagen - hydroxyapatite*
20	*In Vitro Evaluation of the toxicity of thiabendazole on cell lines HN5 (squamous cell carcinoma)*
21	*The effect of caffeine on gene expression of bcl-2 and the average survival rate squamous cell carcinoma and normal oral mucosa*
22	*Determine the relationship between primary second molars as a clinical indicator of growth in patients with radiographic indices referred to orthopedic clinic Imam Khomeini.*
23	*Compare bond strength of conventional methods fixed by screws and plates of bone fragments and the use of bone cement for fixation systems maxillofacial fractures In-vitro environment*
24	*Histopathological Comparison between Bone Marrowand Periodontium-derived Stem Cells for Bone Regeneration in Rabbit Calvaria*
25	*The analysis of blood sugar before and after tooth extraction in patients referred to oral and maxillofacial surgery*
26	*Quality of life and mental health in patients with temporomandibular joint disorders (TMD) (Tmd)*
27	Compare histomorphometric results of the repair Alvgrfthay mineralized tissues such as the construction of Kish, University of tissue banks with bovin (xenograft) and control (empty hole) in rabbit calvaria bone.
28	*Check the accuracy of diagnostic procedures and treatment of patients with oral squamous cell carcinoma (OSCC) referred to the Cancer Institute of Imam Khomeini Hospital during Hay 2002-2013.*
29	*Antibiotic prophylaxis Tasyranty on complications after third molar surgery Analysis -Mta*
30	*Long-term evaluation of masticatory function in condylectomy patiants*
31	*A labratory comparision between miniplates 2mm screws used commonly in fixation of mandibular osteotomy loaded and normal bite force*
32	*Comparing of effects of Diod low level laser therapy 660nm and 810 nm on invasion and proliferation of squamous cell carcinoma-invitro*
33	*Perineural infiltration of the inferior alveolar nerve in mandibular ameloblastoma*
34	*Dental Pulp Stem Cell Differentiation to Odontoblast When Encapsulated in Fibrin Gel Containing Melatonin*
35	*Nasal and upper lip soft tissue changes following by pyriform reshaping in orthognathic(lefort1) surgery*
36	*Development of a 3D model of SCC and analysis of correlation between inhibitory factors (CFH and C4BP) experesion and stemness of SCC to plan a new cure*
37	*Evaluation of the expression level of mir-509-5p, mir-548-3p,mir-561(5), mir-486-3p genes and OGG1 protein in biopsy samples of patients with cancer of oral and maxillofacial region*
38	*A Comparative study to assess feasibility of computer assisted fabricated surgical guides vs. conventional technique in Bilateral Sagittal spilt osteotomy*
39	*Study the effect of photobiomodulation on neural proliferation and differentiation of the wisdom tooth mesenchymal follicle stem cells*
40	*Comparative study between Oral Squamous Cell Carsinoma patiants and healthy people for detection of human papillomavirus and it’s genetic serotypes*
41	*Evaluating the Differentiation of Wharton Jelly-Derived Stem Cells in to Nasal Cartilage on 3D Printed Polycaprolactone Scaffolds with Control Release of Small molecules*
42	Comparison of the nature and strength of the new bone after using benzophenone tatra-carboxylic dianhydride methyl methacrylate containing bone adhesives and conventional plate and screw in New Zeland Rabit mandibular fracture fixation
43	*Osteogenic differention of human priodontal ligamant cells on alginate-calcium scaffold with freez drying*
44	*Study of differentiation of periodontal ligament-derived stem cells to mucinic cells of salivary glands by co-culture method*
45	*The design and fabrication of nerve guid conduit by 3D printing technique for repair of peripheral nerve injury*
46	*Staged approach guided bone regeneration using customized CAD-CAM titanium mesh in partially edentulous ridges - A feasibility study*
47	*Evaluation of expression level of LncRNAs contributing in the signaling pathways: PVT1,CCAT2,TC7L2,MYC and miRNA33*
48	*Investigation of outcomes related to satisfactory rate of Genioplasty in patients reffering to oral and maxillofacial surgery department of Tehran university during the last 10 years*
49	*Comparison the general quality of life of adolescent with cleft lip and palates with and without speech therapy in time of covid 19*
50	Fabrication of poly (ε-caprolactone)-hydroxyapatite scaffolds containing dexamethasone-loaded microparticles and adipose mesenchymal stem cells by 3D bioprinting for craniomaxillofacial bones repair.
51	*Evaluation of hard and soft tissue changes after distraction osteogenesis of maxilla in patients with complete unilateral cleft lip and palate deformity*
52	*Evaluating the impact of Lefort I osteotomy angulation on the position of upper central incisor using Proplan CMF software*
53	Evaluation of anxiety of parents with neonates undergoing nasoalveolar molding and problems occurring during treatment in patients referred to the cleft lip and palate clinic of the School of Dentistry, Tehran University of Medical Sciences during Covid-19 pandemic (a case series study)
54	*Comparison of facial symmetry after surgical reconstruction of segmental defects in mandible using digital and conventional method*
55	*Evaluation Of Patients Awareness Of Dental Considerations And Maxiofacial Side Effects Who Are Using Medications That Related With Osteonecrosis Of The Jaw Bones*
56	*Fabrication of hydrogel scaffolds by extrusion 3D printing method for cartilage regeneration*
57	*In-vtro and in-vivo evaluation of osteoinductive properties of bone condition media (BCM) and particulate autograft during bone augmentation by guided bone regeneration (GBR)*
58	Fabrication of a polymer-based ear prosthesis, using dimensional printers integrated with electronic circuits, capable of sensing temperature and pressure changes and used as a scaffold for keratinocyte cells
59	*Construction of the nose using cartilage cell encapsulating hydrogels with the ability to stimulate the olfactory system with the help of a biosensor*
60	*Evaluation of relationship between Carcinoma Associated Fibroblasts and SOX10 in HPV-related and non-HPV-related oropharyngeal squamous cell carcinoma*
61	*Comparison between nasalance score and acoustic parameters in children with cleft lip and palate and normal*
62	*Retrospective study of providing services to patients with maxillofacial malformations referred to the maxillofacial surgery ward of Shariati Hospital, Tehran University of Medical Sciences*
63	Evaluation of miR-24, miR-125, miR-200, miR-30, miR-34, miR-31, miR-4513 and apoptotic genes and inflammatory cytokines in saliva samples of patients with oral squamous cell carcinoma, Compared with saliva samples from healthy people and peripheral blood
64	*Direct handpiece design for use in maxillofacial micromotor surgery*
65	*Cartilage repair scaffold design with the simultaneous use of mesenchymal cells and exosomes by 3D printing method*
66	*Direct type handpiece manufacturing for use in surgical electric motor*
67	*Bone tissue engineering using Stem Cells from Human Exfoliated Deciduous Teeth(SHED) along with shedderived exosomes on polycaprolactone scaffold by 3D printing method*
68	*Designing the structure of SCfV tetrameric clusters against the PD1 receptor in order to simultaneously induce agonistic and antagonistic effects on the function*
69	*Evaluation of Lysozyme C, Involucrin and B ZG16 proteins in oral tumor tissue by proteomics method and then molecular investigation of these markers by Realtime PCR method*
70	*Clarifying the opinions and experiences of parents of babies with cleft palate and lip referred to the children's medical center*
71	*Optimization of GFP model protein synthesis using Cell free expression system*
72	*Plate Removal and Risk Factors Contributing to Plate-Related Complications Following Rigid Fixation in Maxillofacial Surgery: A Retrospective Study*
73	*Investigating stress and strain inside surgical screws and plates in mandibular trunk fractures in different screw and plate situations: finite element analysis*
74	*Investigation of the effect of hydrophilicity on the adhesion properties of bone adhesive based on polymethyl methacrylate*
75	*The effect of Facial Yoga on the Temporomandibular Disorders*
76	*Comparison of patient specific implants with traditional implants in correction of globe malposition in patients with orbital fractures*
77	*Bone tissue engineering using endometrial mesenchymal stem cells along with osteoblast drived exosomes on polycaprolactone scaffold with collagen by 3D printing method*
78	*Fabrication of temporomandibular joint cartilage using PCL/Gelatin scaffold containing endometrial stem cells with 3D printing method and in vivo bioreactor*
79	Investigating the effect of endometrial cells and vascular endothelial growth factor B loaded in alginate scaffold based on Fmoc-FF peptide on neurogenesis and inflammation in a rat model of Parkinson's disease
80	*3D bioprinting of composite hydrogel scaffold based on GelMA for bone tissue engineering applications*
81	*Evaluation of the efficacy of exosomes extracted from human endothelial stem cells for the treatment of cardiac infarction in an animal model following gingivitis*
82	Investigating the effect of injection of human umbilical cord-derived mesenchymal stem cell exosomes preconditioned by hypoxia on tumor size, cognitive functions, and expression levels of inflammatory and apoptotic factors in glioblastoma model of rats
83	*Synthesis and encapsulation of Equisetum arvense extract with chitosan and their effect on the differentiation of Endometrial stem cells into osteogenic cell*
84	*Examination of TFRC gene expression in oral squamous cell carcinoma patients in comparison with healthy people*
85	*Assessment of NCBP2 expression in patients with oral squamous cell carcinoma (OSCC) in comparison with healthy individuals*
86	*Examination of clinical and pathological characteristics and its relationship with cytogenic changes in patients with cherubism*
87	*The use of biodegradable polycaprolactone-tricalcium phosphate patient-specific prostheses made with a 3D bioprinter in rhinoplasty.*
88	*Investigating modulation of neurogenesis and oxidative stress in Alzheimer's model of rat treated with mesenchymal stem cell exosomes pre-conditioned with hypoxia*
89	*Investigating the anti-photoaging properties of Bacillus subtilis cell extract and extracellular vesicles derived from B. subtilis in human skin fibroblast (HDF) cells model*
90	*Effects of nHA-coated subperiosteal implants on the Expression of ECM-Related Genes in Gingival Fibroblasts*
91	*Investigating the effect of ambient air pollutants on Oral lichen Planus*
92	*Temporomandibular joint load estimation in chewing process using radiology images and deep learning methods*
93	Investigating plasma and brain changes of inflammatory factors and mir-146 and mir-155 biomarkers following treatment with umbilical cord-derived mesenchymal stem cell exosomes in Alzheimer's model in rats
94	Assessment of Low-Level Laser Therapy (Photobiomodulation) Effects on Collagen I and Bone Morphogenegic Protein 2 Osteoblastic Biomarkers and Tartrate-Resistant Acid Phosphatase and Cathepsin K Osteoclastic Biomarkers in Dexamethasone-Treated Bone Tissue Blocks

Research projects

Prevalence of facial fractures in patients referring to Shariati Hospital in Tehran 90

Prevalence of cardiovascular disease in patients with obstructive sleep apnea

Accuracy Astryvftvgramtry system Kranyvmagzylvfyshyal Research Center, Tehran University of Medical Sciences

Effects of orthognathic surgery on quality of life

Cephalometric study of anatomical structures adjacent upper airway in patients with obstructive sleep apnea

Evaluation of facial soft tissue changes with structured light technique to predict the results of orthognathic surgery (BiMax) Class III and three-dimensional modeling software design and implementation

Histologic and histomorphometric effects of alendronic acid and calcium on Astyvayntgryshn femoral implants in rats was Avrktvmy

Induced bone formation in cleft palate using bone inducing protein (BMP-2) in dogs.

Examine factors associated with temporomandibular disorders in patients referred to the department of oral and maxillofacial surgery, Shariati Hospital

Investigate the correlation of clinical and pathological margin squamous cell carcinoma of the mouth

Measured anthropometric soft tissue in the adult population of Iranian foreign

Effect of cinching techniques in pre-surgical nasal lefort I

Prevalence and associated factors in patients with orofacial pain center in Tehran University Hospital

The effect of the synthetic membrane around the mandibular reconstruction plates on the amount of exposure

Evaluation and comparison of the lab and tissue toxicity caused by miniplates common in skull and maxillofacial surger.

IN silico design and production of the carrier structure (RECOMBINANT HUMAN BONE MOROHOGENETIC PROTEIN-2 (RHBMP-2 using genetic engineering in bacteria E.Coli

Expression of genes involved (DKK-1, BMP, β-catenin, sclerostin and Noggin) on routes bone growth in patients with unilateral development of temporomandibular joint condyle.

Optimize the BMP2 protein expression in E.Coli host

Pvrmvrfamyn the effect on osteogenic differentiation of endometrial stem cells on scaffolds of collagen - hydroxyapatite

In Vitro Evaluation of the toxicity of thiabendazole on cell lines HN5 (squamous cell carcinoma)

The effect of caffeine on gene expression of bcl-2 and the average survival rate squamous cell carcinoma and normal oral mucosa

Determine the relationship between primary second molars as a clinical indicator of growth in patients with radiographic indices referred to orthopedic clinic Imam Khomeini.

Compare bond strength of conventional methods fixed by screws and plates of bone fragments and the use of bone cement for fixation systems maxillofacial fractures In-vitro environment

Histopathological Comparison between Bone Marrowand Periodontium-derived Stem Cells for Bone Regeneration in Rabbit Calvaria

The analysis of blood sugar before and after tooth extraction in patients referred to oral and maxillofacial surgery

Quality of life and mental health in patients with temporomandibular joint disorders (TMD) (Tmd)

Compare histomorphometric results of the repair Alvgrfthay mineralized tissues such as the construction of Kish, University of tissue banks with bovin (xenograft) and control (empty hole) in rabbit calvaria bone.

Check the accuracy of diagnostic procedures and treatment of patients with oral squamous cell carcinoma (OSCC) referred to the Cancer Institute of Imam Khomeini Hospital during Hay 2002-2013.

A labratory comparision between miniplates 2mm screws used commonly in fixation of mandibular osteotomy loaded and normal bite force

Comparing of effects of Diod low level laser therapy 660nm and 810 nm on invasion and proliferation of squamous cell carcinoma-invitro

Perineural infiltration of the inferior alveolar nerve in mandibular ameloblastoma

Dental Pulp Stem Cell Differentiation to Odontoblast When Encapsulated in Fibrin Gel Containing Melatonin

Nasal and upper lip soft tissue changes following by pyriform reshaping in orthognathic(lefort1) surgery

Evaluation of the expression level of mir-509-5p, mir-548-3p,mir-561(5), mir-486-3p genes and OGG1 protein in biopsy samples of patients with cancer of oral and maxillofacial region

A Comparative study to assess feasibility of computer assisted fabricated surgical guides vs. conventional technique in Bilateral Sagittal spilt osteotomy

Study the effect of photobiomodulation on neural proliferation and differentiation of the wisdom tooth mesenchymal follicle stem cells

Comparative study between Oral Squamous Cell Carsinoma patiants and healthy people for detection of human papillomavirus and it’s genetic serotypes

Evaluating the Differentiation of Wharton Jelly-Derived Stem Cells in to Nasal Cartilage on 3D Printed Polycaprolactone Scaffolds with Control Release of Small molecules

Comparison of the nature and strength of the new bone after using benzophenone tatra-carboxylic dianhydride methyl methacrylate containing bone adhesives and conventional plate and screw in New Zeland Rabit mandibular fracture fixation

Osteogenic differention of human priodontal ligamant cells on alginate-calcium scaffold with freez drying

Study of differentiation of periodontal ligament-derived stem cells to mucinic cells of salivary glands by co-culture method

The design and fabrication of nerve guid conduit by 3D printing technique for repair of peripheral nerve injury

Staged approach guided bone regeneration using customized CAD-CAM titanium mesh in partially edentulous ridges - A feasibility study

Evaluation of expression level of LncRNAs contributing in the signaling pathways: PVT1,CCAT2,TC7L2,MYC and miRNA33

Investigation of outcomes related to satisfactory rate of Genioplasty in patients reffering to oral and maxillofacial surgery department of Tehran university during the last 10 years

Comparison the general quality of life of adolescent with cleft lip and palates with and without speech therapy in time of covid 19

Fabrication of poly (ε-caprolactone)-hydroxyapatite scaffolds containing dexamethasone-loaded microparticles and adipose mesenchymal stem cells by 3D bioprinting for craniomaxillofacial bones repair.

Evaluation of hard and soft tissue changes after distraction osteogenesis of maxilla in patients with complete unilateral cleft lip and palate deformity

Evaluating the impact of Lefort I osteotomy angulation on the position of upper central incisor using Proplan CMF software

Evaluation of anxiety of parents with neonates undergoing nasoalveolar molding and problems occurring during treatment in patients referred to the cleft lip and palate clinic of the School of Dentistry, Tehran University of Medical Sciences during Covid-19 pandemic (a case series study)

Comparison of facial symmetry after surgical reconstruction of segmental defects in mandible using digital and conventional method

Evaluation Of Patients Awareness Of Dental Considerations And Maxiofacial Side Effects Who Are Using Medications That Related With Osteonecrosis Of The Jaw Bones

Fabrication of hydrogel scaffolds by extrusion 3D printing method for cartilage regeneration

In-vtro and in-vivo evaluation of osteoinductive properties of bone condition media (BCM) and particulate autograft during bone augmentation by guided bone regeneration (GBR)

Fabrication of a polymer-based ear prosthesis, using dimensional printers integrated with electronic circuits, capable of sensing temperature and pressure changes and used as a scaffold for keratinocyte cells

Construction of the nose using cartilage cell encapsulating hydrogels with the ability to stimulate the olfactory system with the help of a biosensor

Evaluation of relationship between Carcinoma Associated Fibroblasts and SOX10 in HPV-related and non-HPV-related oropharyngeal squamous cell carcinoma

Comparison between nasalance score and acoustic parameters in children with cleft lip and palate and normal

Retrospective study of providing services to patients with maxillofacial malformations referred to the maxillofacial surgery ward of Shariati Hospital, Tehran University of Medical Sciences

Evaluation of miR-24, miR-125, miR-200, miR-30, miR-34, miR-31, miR-4513 and apoptotic genes and inflammatory cytokines in saliva samples of patients with oral squamous cell carcinoma, Compared with saliva samples from healthy people and peripheral blood

Direct handpiece design for use in maxillofacial micromotor surgery

Cartilage repair scaffold design with the simultaneous use of mesenchymal cells and exosomes by 3D printing method

Direct type handpiece manufacturing for use in surgical electric motor

Bone tissue engineering using Stem Cells from Human Exfoliated Deciduous Teeth(SHED) along with shedderived exosomes on polycaprolactone scaffold by 3D printing method

Designing the structure of SCfV tetrameric clusters against the PD1 receptor in order to simultaneously induce agonistic and antagonistic effects on the function

Evaluation of Lysozyme C, Involucrin and B ZG16 proteins in oral tumor tissue by proteomics method and then molecular investigation of these markers by Realtime PCR method

Clarifying the opinions and experiences of parents of babies with cleft palate and lip referred to the children's medical center

Optimization of GFP model protein synthesis using Cell free expression system

Plate Removal and Risk Factors Contributing to Plate-Related Complications Following Rigid Fixation in Maxillofacial Surgery: A Retrospective Study

Investigating stress and strain inside surgical screws and plates in mandibular trunk fractures in different screw and plate situations: finite element analysis

Investigation of the effect of hydrophilicity on the adhesion properties of bone adhesive based on polymethyl methacrylate

The effect of Facial Yoga on the Temporomandibular Disorders

Comparison of patient specific implants with traditional implants in correction of globe malposition in patients with orbital fractures

Bone tissue engineering using endometrial mesenchymal stem cells along with osteoblast drived exosomes on polycaprolactone scaffold with collagen by 3D printing method

Fabrication of temporomandibular joint cartilage using PCL/Gelatin scaffold containing endometrial stem cells with 3D printing method and in vivo bioreactor

Investigating the effect of endometrial cells and vascular endothelial growth factor B loaded in alginate scaffold based on Fmoc-FF peptide on neurogenesis and inflammation in a rat model of Parkinson's disease

3D bioprinting of composite hydrogel scaffold based on GelMA for bone tissue engineering applications

Evaluation of the efficacy of exosomes extracted from human endothelial stem cells for the treatment of cardiac infarction in an animal model following gingivitis

Investigating the effect of injection of human umbilical cord-derived mesenchymal stem cell exosomes preconditioned by hypoxia on tumor size, cognitive functions, and expression levels of inflammatory and apoptotic factors in glioblastoma model of rats